科研項目

 

　　1)油溶性維生素C脂肪酸酯合成的研究，企事業(yè)單位委托技術(shù)開發(fā)項目

 

　　2)新型[膽堿][氨基酸]離子液體預(yù)處理對木質(zhì)纖維素酶解反應(yīng)的影響機理(2014ZG0045)，中央高?；究蒲袠I(yè)務(wù)費項目

 

　　3)含DES介質(zhì)中β-糖苷酶催化二糖核苷合成的研究(2012J2200011)，珠江科技新星專項

 

　　4)新型[膽堿][氨基酸]離子液體預(yù)處理水稻秸稈過程及其機理研究(y207k31001)，廣州能源所開放基金

 

　　5)微生物細(xì)胞催化樺木醇選擇性氧化合成樺木酸的關(guān)鍵技術(shù)研究（2010B011000003），廣東省科技計劃項目

 

　　6)含深度共熔溶劑（DES）介質(zhì)中β-葡萄糖苷酶催化核苷葡萄糖基化反應(yīng)的研究（20906032），國家自然科學(xué)基金

　　學(xué)術(shù)論文

 

　　近3年發(fā)表的主要論文

 

　　1）Hou XD, Xu J,Li N, Zong MH. Effect of anion structures on cholinium ionic liquidspretreatment of rice straw and the subsequent enzymatic hydrolysis. Biotechnol.Bioeng., 2014, DOI:10.1002/bit.25335

 

　　2）An YX, Li N, Zong MH, Lou WY.Easily measurable pH as an indicator of aqueous cholinium ionic liquidpretreatment effectiveness of lignocellulose. RSC Adv., 2014, 4 (98): 55635-55639

 

　　3）Hu YD, Qin YZ,Li N, Zong MH. Highly efficient enzymatic synthesis of an ascorbyl unstaturatedfatty acid ester with ecofriendly biomass-derived 2-methyltetrahydrofuran asco-solvent. Biotechnol. Prog., 2014,30 (5): 1005-1011

 

　　4）Yan LQ, Li N, Zong MH. Firstenzymatic galactosylation of acyclic nucleoside drugs by β-galactosidase:Synthesis of water-soluble β-D-galactosidic prodrugs. Biotechnol. BioprocessEng., 2014, 19 (4): 586-591

 

　　5）Hou XD, Li N,Zong MH. Renewable bio ionic liquids-water mixtures-mediated selecive removalof lignin from rice straw: Visualization of changes in composition and cellwall structure. Biotechnol. Bioeng., 2013,110 (7): 1895-1902

 

　　6）Hou XD, Li N,Zong MH. Significantly enhancing enzymatic hydrolysis of rice straw afterpretreatment using renewable ionic liquid-water mixtures. Bioresour. Technol., 2013, 136 469-474

 

　　7）Hou XD, Li N,Zong MH. Facile and simple pretreatment of sugar cane bagasse without sizereduction using renewable ionic liquids-water mixtures. ACS Sustainable Chem.Eng., 2013, 1 (5): 519-526

 

　　8）Hou XD, Liu QP,Smith TJ, Li N, Zong MH. evaluation of toxicity and biodegradability ofcholinium amino acids ionic liquids. PloS one, 2013, 8 (3): e59145

 

　　9）Liu H, Lei XL,Li N, Zong MH. Highly regioselecive synthesis of betulone from betulin bygrowing cultures of marine fungus Dothideomycetesp. HQ 316564. J. Mol. Catal. B: Enzym., 2013,88: 32-35

 

　　10）Gao WL, Li N,Zong MH. Enzymatic regioselecive acylation of nucleosides in biomass-derived2-methyltetrahydrofuran: kinetic study and enzyme substrate recognition. J.Biotechnol., 2013, 164 (1): 91-96

 

　　11）Liu QP, Hou XD,Li N, Zong MH. Ionic liquids from renewable biomaterials: synthesis,characterization and application in the pretreatment of biomass. Green Chem., 2012, 14 (2): 304-307

 

　　12）Hou XD, SmithTJ, Li N, Zong MH. Novel renewable ionic liquids as highly effective solventsfor pretreatment of rice straw biomass by selecive removal of lignin.Biotechnol. Bioeng., 2012, 109 (10):2484-2493

 

　　13）Gao WL, Liu H,Li N, Zong MH. Regioselective enzymatic undecylenoylation of 8-chloroadenosineand its analogs with biomass-based 2-methyltetrahydrofuran as solvent.Bioresour. Technol., 2012, 118 82-88

 

　　14）Ye M, Yan LQ,Li N, Zong MH. Facile and regioselective enzymatic 5'-galactosylation ofpyrimidine 2'-deoxynucleosides catalyzed by β-glycosidase from bovine liver. J.Mol. Catal. B: Enzym., 2012, 7935-40

 

　　15）Yang RL, Li N,Zong MH. Using ionic liquid cosolvents to improve enzymatic synthesis ofarylalkyl β-D-glucopyranosides. J. Mol. Catal. B: Enzym., 2012, 74 (1-2): 24-28

 

　　16）Yan LQ, Li N,Zong MH. First and facile enzymatic synthesis of β-fucosyl-containingdisaccharide nucleosides through β-galactosidase-catalyzed regioseleciveglycosylation. J. Biotechnol., 2012,164 (2): 371-375

 

　　17）Liu X, Wei W,Yuan Q, Zhang X, Li N, Du Y, Ma G, Yan C, Ma D. Apoferritin-CeO2 nano-trufflethat has excellent artificial redox enzyme activity. Chem. Commun., 2012, 48 (26): 3155-3157

 

　　18）Gao WL, Liu H,Li N, Zong MH. Regioselective enzymatic undecylenoylation of 8-chloroadenosineand its analogs with biomass-based 2-methyltetrahydrofuran as solvent.Bioresour. Technol., 2012, 118 82-88

 

　　Chen L, Li N, Zong MH. A Glucose-tolerantβ-glucosidase from Prunus domestica seeds: purification and characterization.Process Biochem., 2012, 47 (1):127-132

 

　　獲獎

 

　　1)2009年廣東省優(yōu)秀博士學(xué)位論文獎

 

　　2)2010年全國優(yōu)秀博士學(xué)位論文提名論文獎

 

　　3)2012年廣州市珠江科技新星

 

　　4)2013年廣東省自然科學(xué)二等獎(排名第4)