研究方向及承擔(dān)課題

　　運(yùn)用納米技術(shù)、生物技術(shù)等從事食品活性物質(zhì)、生物大分子(如核酸、多糖、蛋白質(zhì)等)等功能材料的開發(fā)與應(yīng)用，主要包括納米自組裝載體系統(tǒng)、納米水凝膠系統(tǒng)、納米乳等。

　　主持項(xiàng)目：水分散型天然蝦青素/核酸/殼聚糖納米復(fù)合體的研究（國(guó)家自然科學(xué)基金，2014-2016）；親水性蝦青素納米營(yíng)養(yǎng)載運(yùn)體系的構(gòu)建與轉(zhuǎn)運(yùn)吸收研究（中國(guó)博士后面上基金，2014-2016）

　　參與項(xiàng)目：生物材料微觀軟結(jié)構(gòu)對(duì)皮膚組織再生修復(fù)過(guò)程的作用（國(guó)家自然科學(xué)基金，2014-2016）；靶向納米載藥體系的透粘膜性及抗乳腺癌作用（國(guó)家自然科學(xué)基金，2011-2013）；皮膚組織再生修復(fù)復(fù)方水凝膠體系的構(gòu)建（國(guó)家自然科學(xué)基金，2011-2013）。

　　近期發(fā)表相關(guān)論著列表

　　1) Jing Li, Fangkui Ma,Qifeng Dang,Xingguo Liang,Xiguang Chen.Glucose-conjugatedchitosan nanoparticles for targeted drug delivery and their specificinteraction with tumor cells. Frontiers ofMaterials Science.DOI: 10.1007/s11706-014-0262-8, 2014.

　　2)Jing Li,Xingyu Wang, Xingguo Liang. Modification of Nucleic Acids by AzobenzeneDerivatives and Their Applications in Biotechnology and Nanotechnology. ChemAsian J. DOI: 10.1002/asia.201402758, 2014.

　　3) Wei Fang Liu, Hui Di Zang,Xuan Zhou, Chuan Zhen Kang, Yang Li, JingLi, Qi Feng Dang, Xiao Jie Cheng, Xi Guang Chen. The primary culture andsubculture of lymphoid cells from shrimp, Penaeuschinensis on thermo-sensitive CS/α, β-GP hydrogel. Aquac Res.45(2):334-340, 2014.

　　4) Xingguo Liang, Jing Li. Biotechnology ofAzobenzene-Modified DNA and RNA. International conference on appliedbiotechnology, LNEE. 251: (1317-1331), 2013.

　　5) Kui Kun Yang, Ming Kong, YaNan Wei, Ya Liu, Xiao Jie Cheng, Jing Li,Hyun Jin Park, Xi Guang Chen. Folate modified chitosan coated liposomes fortumor-targeted drug delivery. J Mater Sci. 48(4): 1717-1728, 2013.

　　6) Fang Kui Ma,Jing Li, Ming Kong,Ya Liu, Yi An, Xi Guang Chen. Preparation and hydrolytic erosion of differentlystructured PLGA nanoparticles with chitosan modification. Int J Biol Macromol. 54: 174-179, 2013.

　　7) Xuan Zhou, Xiao Jie Cheng, WeiFang Liu, Jing Li, Li Hong Ren, QiFeng Dang, Chao Feng, Xi Guang Chen. Optimization andcharacteristics of preparing chitosan microspheres using response surfacemethodology. J Appl Polym Sci. 127(6): 4433-4439, 2013.

　　8) Jing Li, Ming Kong, Xiao Jie Cheng, Qi Feng Dang, Xuan Zhou, YaNan Wei, Xi Guang Chen. Preparation of biocompatible chitosan graftedpoly(lactic acid) nanoparticles. Int J Biol Macromol. 51(3): 221– 227, 2012.

　　9）臧惠迪, 程曉杰, 李陽(yáng), 李敬, 陳西廣. 殼聚糖/αβ-甘油磷酸凝膠微球的制備及性質(zhì)研究. 中國(guó)海洋大學(xué)學(xué)報(bào). 42(9): 35-40, 2012.

　　10) Jing Li, Ming Kong, XiaoJie Cheng, Jing Jing Li, Wei Fang Liu, Xi Guang Chen. Afacile method for preparing biodegradable chitosan derivative with low graftingdegree of poly (lactic acid). Int J Biol Macromol. 49(5): 1016– 1021, 2011.

　　發(fā)明專利列表

　　1）李敬, 梁興國(guó), 萬(wàn)百惠. 一種應(yīng)用天然核酸制備的微/納米載體及其制備方法. 2013.11, 受理號(hào)201310544906.5.

　　2）陳西廣,李敬,程曉杰,江濤.胺糖化幾丁聚糖復(fù)合物的制備方法.2011.7, 中國(guó),ZL 200810238392. X.

　　3）Xiguang Chen, Jing Li, Xiaojie Cheng, Tao Jiang. Process for preparing compoundsof chitosan saccharified with aminosugar. 2012.7, USA, US008202971.