代表性論文（* 通訊作者；# 共同第一作者）

 

　　1.Wu Y, Yang Y, Ye S, Jiang Y. (2010) Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+-gated K+ Channel. Nature  466(7304):393-7.

 

　　2.Wu Y, Sha B. (2006). Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p. Nature Structural & Molecular Biology  13(7):589-93.

 

　　3.Li S, Zhao Y, Zhao Z, Wu X, Sun L, Liu Q, Wu Y*. (2016) Crystal structure of GRAS domain of SCARECROW-LIKE 7 in Oryza sativa. Plant Cell  2016 May;28(5):1025-34 DOI: 10.1105/tpc.16.00018 (highlighted article, 生物1區(qū)； IF 9.338)

 

　　4.Zhang L, Zeng Z, Hu C, Bellis SL, Yang W, Su Y, Zhang X, Wu Y*. (2016) Controlled and targeted release of antigens by intelligent shell for improving applicability of oral vaccines. Biomaterials 2016 Jan;77:307-19. doi: 10.1016/j.biomaterials.2015.11.009. (生物材料1區(qū)；IF：8.557)

 

　　5.Zhang L*, Fan Y, Wu Y*. (2014) Inositol based none-viral vectors for transgene expression in human cervical carcinoma and hepatoma cell lines. Biomaterials  2014 Feb;35(6):2039-50. doi: 10.1016/j.biomaterials.2013.11.034.  (生物材料1區(qū)；IF：8.557)

 

　　6.A luminescent layered hybrid Ag–Ru/LDH as a photocatalytic antibacterial agent. Fangnan Xiao, Xiaolin Liu, Yue Xiao, Fangman Chen，Yunkun Wu*. New Journal of Chemistry 2017 June 41 7260-7266

 

　　7.Sun L, Chen P, Su Y, Cai Z, Ruan L, Xu X, Wu Y*. Crystal structure of thermostable alkylsulfatase SdsAP fromPseudomonas sp. S9.Biosci Rep. 2017 May 11;37(3) doi: 10.1042/BSR20170001.

 

　　8.Crystal structure of the type IV secretion system component CagX from Helicobacter pylori.Zhang J, Fan F, Zhao Y, Sun L, Liu Y, Keegan RM, Isupov MN, Wu Y*.Acta Crystallogr F Struct Biol Commun. 2017 Mar 1;73(Pt 3):167-173. doi:10.1107/S205323017001376. Epub 2017 Feb 28.

 

　　9.Lifang Sun, Yintao Su, Yanhe Zhao, Zheng-qing Fu, Yunkun Wu*.（2016）Crystal Structure of Major Envelope Protein VP24 from White Spot Syndrome Virus. Scientific Reports.2016 Aug 30;6:32309. doi: 10.1038/srep32309. (IF 5.228)

 

　　10.Zhang L, Hu C, Yang W, Liu X, Wu Y*. （2016）Chemical synthesis, versatile structures and functions of tailorable adjuvants for optimizing oral vaccination. ACS Appl Mater Interfaces. 2016 Dec 28;8(51):34933-34950. doi: 10.1021/acsami.6b10470  (工程技術(shù)一區(qū)；IF: 7.145)

 

　　11.Shengping Li, Yintao Su, Yadan Liu, Lifang Sun, Minxiang Yu, Yunkun Wu*. （2016）Preparation and characterization of cross-linked enzyme aggregates (CLEAs) of recombinant thermostable alkylsulfatase (SdsAP) from Pseudomonas sp. S9. Process Biochemistry51(12)：2084–2089. DOI：10.1016/j.procbio.2016.09.013

 

　　12.Lifang Sun, Yunkun Wu*. (2016) Envelope protein VP24 from White spot syndrome virus: expression, purification and crystallization.Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):586-90. doi: 10.1107/S205323016009055.

 

　　13.Xianren Ye, Yanhe Zhao, Xiuling Wu, Yintao Su, Yunkun Wu*, Feifei She*. (2015) Identification of residues involved in nucleotidyltransferase activity of JHP933 from helicobacter pyloriby site-directed mutagenesis. Archives of Biological Sciences 01/2015; DOI:10.2298/ABS150622127Y

 

　　14.Su Y, Shi F, Zeng Z, Wu X, Zhao Y, Zhang L, Xie Z*, Wu Y*.(2015) A Versatile Monoclonal Antibody Specific Against Human DAB2IP.Monoclon Antib Immunodiagn Immunother. Aug;34(4):246-50. doi: 10.1089/mab.2015.0012.

 

　　15.Zhang L*, Bellis SL, Fan Y, Wu Y*. (2015) Using Inositol as a Biocompatible Ligand for Efficient Transgene expression.International Journal of Nanomedicine. 2015:10 2871-84. (工程技術(shù)一區(qū)；IF: 4.32)

 

　　16.Zhao Y, Ye X, Su Y, Sun L, She F*, Wu Y*. (2014) Crystal structure confirmation of JHP933 as a nucleotidyltransferase superfamily protein from Helicobacter pylori strain J99. PLoS One 2014 Aug 7;9(8):e104609. doi: 10.1371/journal.pone.0104609.

 

　　17.Zhang L*, Hu C, Fan Y, Wu Y*. (2013) Binary gene vectors based on hyperbranched poly(L-lactide-co-polyglycerol) and polyethylenimine for prolonged transgene expression via co-assembly with DNA into fiber core–shell triplexes.  J. Mater. Chem. B1(45), 6271-6282  (工程技術(shù)一區(qū)；IF: 6.627)

 

　　18.Li J#, Wu Y*, Qian X, Sha B. (2006). Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex. Biochemical Journal398(3): 353-60.

 

　　19.Wu Y, McCombs D, Nagy L, Delucas L, Sha B. (2006). Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 62(Pt 3):265-7.

 

　　20.Wu Y, Li J, Jin Z, Fu Z, Sha B. (2005). The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40. Journal of Molecular Biology 346(4):1005-11.

 

　　21.Tao J, Wu Y, Ron D, Sha B. (2008). Preliminary X-ray crystallographic studies of mouse UPR responsive protein P58 (IPK) TPR fragment.Acta Crystallogr Sect F Struct Biol Cryst Commun. 64(Pt 2):108-10.

 

　　22.Hu J, Wu Y, Li J, Qian X, Fu Z, Sha B. (2008) The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1. BMC Structural Biology 8:3.

 

　　發(fā)明專利

 

　　1．一種用于PEI等陽(yáng)離子聚合物介導(dǎo)轉(zhuǎn)染的聚酯保護(hù)殼層的熔融超聲自組裝制備技術(shù)申請(qǐng)?zhí)?201310642103.3

 

　　2. 一種抗人DAB2IP的單克隆抗體及其細(xì)胞株  申請(qǐng)?zhí)枺?01410009739.9

 

　　3．一種DAB2IP蛋白的ELISA檢測(cè)方法 (已授權(quán))  申請(qǐng)?zhí)枺篫L 201410052911.9

 

　　4．一種大腸桿菌分泌表達(dá)外源蛋白的質(zhì)粒載體的構(gòu)建 （已授權(quán)）  申請(qǐng)?zhí)枺?01410070632.5

 

　　5.一種pH敏感的雙殼層載藥緩釋體系及其制備方法和用途申請(qǐng)?zhí)枺篊N201510063237.9

 

　　6.一種口服納米疫苗運(yùn)載體的免疫實(shí)施與檢測(cè)技術(shù)申請(qǐng)?zhí)枺?01510729106X。

 

　　7.一種釕配合物聯(lián)合納米銀復(fù)合水滑石型納米材料及其制備方法和用途申請(qǐng)?zhí)枺篊N201610910246.1

 

　　8.一種識(shí)別重金屬銅離子的熒光探針及其合成和應(yīng)用申請(qǐng)?zhí)枺?01710408711.6