張井巖

個人簡介
科研項目
學(xué)術(shù)論文
獲獎
專利
承擔(dān)教學(xué)
研究生培養(yǎng)

姓名：張井巖	性別：
民族：	年齡：
最高學(xué)歷：	學(xué)位：
2000年在以色列魏茲曼科學(xué)研究所獲博士學(xué)位，2000-2001在美國明尼蘇達大學(xué)化學(xué)系做博士后，2001-2003 年在美國明尼蘇達大學(xué)生物化學(xué)系做博士后，隨后在美國明尼蘇達大學(xué)生物化學(xué)系任研究員, 2006年回國加盟華東理工大學(xué)藥學(xué)院，現(xiàn)任華東理工大學(xué)藥學(xué)院藥物科學(xué)系教授。研究成果先后在在國際學(xué)術(shù)刊物J. Am. Chem. Soc., J. Biol. Chem., Chem. Comm., Biochemistry, J. Phys. Chem. Langmuir等）上發(fā)表。主持了三項國家自然科學(xué)基金、上海市科委人才計劃，生物工程反應(yīng)器重點實驗室項目, 國際合作項目等科研項目。　　近年來主要從事化學(xué)生物學(xué)方面的研究，具體包括含金屬離子的酶以及金屬離子與生物大分子的相互作用及其應(yīng)用。

　　代表性論文：

　　1．Ren, Hongliu; Wang, Chong; Zhang, Jiali; Zhou, Xuejiao; Xu, Dafeng; Zheng, Jing; Guo, Shouwu; Zhang, Jingyan. DNA Cleavage System of Nanosized Graphene Oxide Sheets and Copper Ions. ACS Nano 2010, 4, 7169-7174.

　　2. Feng Zhang, Bin Zheng, Jiali Zhang, Xuelei Huang, Hui Liu, Shouwu Guo, Jingyan Zhang* Horseradish Peroxidase Immobilized on Graphene Oxide: Physical Properties and Applications in Phenolic Compound Removal.

　　J. Phys. Chem. C, 2010, 114, 8469–8473

　　3. Jiali Zhang, Feng Zhang, Haijun Yang, Xuelei Huang, Hui Liu, Jingyan Zhang* Shouwu Guo, Graphene Oxide as a Matrix for Enzyme Immobilization.

　　Langmuir 2010, 26, 6083–6085.

　　4. Rong Li, Fuqiang Huang, Xiaojun Jiang, Minyuan Liu, Yanying Song, Hui Liu,Jingyan Zhang* Catalase-like Catalytic Reaction of the Dinuclear Manganese-salen Complex

　　J. Coord. Chem. 2010, 63，1611-1618

　　5. Guanke Zuo, Xiaojun Jiang, Hui Liu,Jingyan Zhang*

　　A Novel Urinary Oxalate Determination Method via a Catalase Model Compound with Oxalate Oxidase

　　Analytical Methods 2010, 2, 254–258

　　6. Jiali Zhang, Haijun Yang, Guangxia Shen, Ping Cheng, Jingyan Zhang* Shouwu Guo, Reduction of graphene oxide via L-ascorbic acid

　　Chem. Commun., 2010, 46, 1112–1114

　　7. Hui Liu, Jinlei Tian, Yingying Kou, Jingyan Zhang, Li Feng, Dongdong Li, Wen Gu, Xin Liu, Daizheng Liao, Peng Cheng, Joan Ribas and Shiping Yan, Synthesis, structures and magnetic properties of polynuclear mixed-valence MnIIMnIII complexes containing 3-(2-phenol)-5-(pyridin-2-yl)-1,2,4-triazole ligand

　　Dalton Trans., 2009, 10511–10517

　　8. Xiaojun Jiang, Hui Liu, Bing Zheng and Jingyan Zhang, Coordination modes of bridge carboxylates in dinuclear manganese compounds determine their catalase-like activities

　　Dalton Trans., 2009, 8714–8723.

　　9. Jing Hou, Guanke Zuo, Guangxia Shen, He Guo, Hui Liu, Ping Cheng, Jingyan Zhang*, Shouwu Guo

　　Hollow Sodium Tungsten Bronze (Na0.15WO3) Nanospheres: Preparation, Characterization, and Their Adsorption Properties

　　Nanoscale Res. Lett. 2009, 4, 1241–1246.

　　10. Jingyan Zhang, John Lipscomb.

　　Mapping the binding conformation of B component to hydroxylase in soluble methane monooxygenase using Spin Labeling EPR spectroscopy

　　Biochemistry 2006, 45，2913-2926

　　11. Jingyan Zhang, John Lipscomb.

　　Role of the C-terminal Region of the B Component of Methylosinus trichosporium OB3b Methane Monooxygenase in the Regulation of Oxygen Activation Biochemistry 2006, 45, 1459-1469

　　12. Jingyan Zhang, Hui Zheng, Stecphen Groce, John Lipscomb

　　Basis for specificity in methane monooxygenase and related non-heme　iron-containing biological oxidation catalysts

　　J. Mol. Cat. A: Chemical 2006， 251, 54-65.

　　13. Aimin Liu, Yi Jin, Jingyan Zhang, Brain Brazeau, John Lipscomb

　　Substrate radical intermidiates in soluable methane monooxygenase

　　Biochem. Biophy. Res. Commun. 2005, 338, 254-261

　　14. Patzlaff, J. S.; Zhang, J.; Brooker, R. J.; Barry, B. A.

　　An Isotope-edited FT-IR Study of a Symporter, the Lactose Permease.

　　Biochemistry 2002, 41, 7366-7372,

　　15. Zhang, J.; Patzlaff, J; Brooker, RJ, et al.

　　FT-IR study of the isotope labelled lactose permease of E-coli

　　Biophysical Journal 2002, 82, 532A.

　　16. DiDonato, M.; Zhang, J.; Que, L. Jr.; and Sarkar, B.

　　Zinc Binding to the N-Terminal Domain of the Wilson Disease Copper-Transporting ATPase: Implications for in vivo metal Ion Mediated Regulation of ATPase Activity.

　　J. Biol. Chem. 2002, 277, 13409.

　　17. Zhang, J.; Carl, P. J.; Zimmerman, H.; Goldfarb, D.

　　Investigation of the formation of MCM-41 by Electron Spin Echo Envelope Modulation spectroscopy.

　　J. Phys. Chem. B 2002, 106, 5382.

　　18. Zhang, J.; Goldfarb, D.

　　In-situ investigation of the Formation mechanism of mesoporous materials

　　via the dynamics and ordering of spin-probes-pH and Si/surfactant effect.

　　Microporous Mesoporous Mater. 2001, 48, 143..

　　19. Zhang, J.; Goldfarb, D.

　　Manganese incorporation into the MCM-41 under acidic conditions and studies by high field EPR and ENDOR techniques

　　J. Am. Chem. Soc. 2000, 122, 7034..

　　20. Zhang, J.; Luz, Z.; Goldfarb, D.

　　Evolution of the rotational diffusion rates and order parameters during the formation of MCM-41

　　J. Phys. Chem. B 2000,104, 279.

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張井巖